3-HYDROXY-3-METHYLGLUTARIC ACID

  • Name: 3-HYDROXY-3-METHYLGLUTARIC ACID
  • CAS: 503-49-1
  • Purity: 99%
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1.What is the 3-HYDROXY-3-METHYLGLUTARIC ACID ?

3-Hydroxy-3-methylpentane-1,5-dioic Acid (cas# 503-49-1) is a compound useful in organic synthesis.

mevalonolactone
674-26-0,503-48-0

mevalonolactone

meglutol
503-49-1

meglutol

Conditions
Conditions Yield
With nitric acid; sodium nitrite; at 35 - 40 ℃; for 5h;
76%
With nitric acid; at 40 ℃; for 4h; Cooling with ice;
57%
3-methyl-1,3,5-pentanetriol
7564-64-9

3-methyl-1,3,5-pentanetriol

meglutol
503-49-1

meglutol

Conditions
Conditions Yield
In acetic acid butyl ester; nitric acid;
85%

2.What is the CAS number for 3-HYDROXY-3-METHYLGLUTARIC ACID ?

The CAS number of 3-HYDROXY-3-METHYLGLUTARIC ACID is 503-49-1.

More information of 3-HYDROXY-3-METHYLGLUTARIC ACID 503-49-1 are:

CAS?Number

503-49-1

Density

1.417 g/cm3

Melting Point

105-108 °C(lit.)

Boiling Point

354.3 °C at 760 mmHg

Flash Point

182.2 °C

Vapor Pressure

1.35E-08mmHg at 25°C

Refractive Index

1.4230 (estimate)

HS CODE

2918199090

PSA

94.83000

LogP

-0.31320

Pka

3.95±0.10(Predicted)

3.What are another words for 3-HYDROXY-3-METHYLGLUTARIC ACID ?

Synonyms?for?3-HYDROXY-3-METHYLGLUTARIC ACID 503-49-1:Glutaricacid, 3-hydroxy-3-methyl- (6CI,7CI,8CI); 3-Hydroxy-3-methylglutaric acid;3-Hydroxy-3-methylpentanedioic acid; 3-Methyl-3-hydroxyglutaric acid;3-Methyl-3-hydroxypentanedioic acid; CB 337; Dicrotalic acid; HMG; HMGA;Lipoglutaren; Medroglutaric acid; Meglutol; Mevalon; NSC 361411; b-Hydroxy-b-methylglutaric acid

4.What is the molecular formula of 3-HYDROXY-3-METHYLGLUTARIC ACID?

The chemical formula of ?3-HYDROXY-3-METHYLGLUTARIC ACID is?C6H10 O5 which containing 6 Carbon atoms,10 Hydrogen atoms and 5 Oxygen atoms,and the molecular weight of??3-HYDROXY-3-METHYLGLUTARIC ACID?is 162.142.

5.What is 3-HYDROXY-3-METHYLGLUTARIC ACID (503-49-1) used for?

Meglutol (β-hydroxy-β-methylglutaric acid; HMG) is a hypolipidemic agent that acts via the inhibition of cholesterol synthesis a t the stage of HMG-CoAreductase, blocking the conversion of HMG-CoA to mevalonate. This conversion is the rate-limiting step in cholesterol biosynthesis and is the point of physiological feedback control; as such, it appears to be the ideal locus of action for a hypolipidemic agent. Investigational compounds that act by this mechanism include the natural products compactin and mevinolin.

InChI:InChI=1/C6H10O5/c7-3-4(1-5(8)9)2-6(10)11/h4,7H,1-3H2,(H,8,9)(H,10,11)

Relevant articles related to 3-HYDROXY-3-METHYLGLUTARIC ACID:

Article

Source

Steroidal glycosides from Allium cyrillii Bulbs

Tolkacheva,Shashkov,Chirva

, p. 272 - 275 (2012)

Hydrolysis of 3-Hydroxy-3-methylglutaronitrile; A Convenient Synthesis of 3-Hydroxy-3-methylglutaric Acid

Yavrouian, Andre H.,Sanchez, Robert A.,Pollard, John K.,Metzner, E. Kurt

, p. 791 - 793 (1981)

6.Buy 3-HYDROXY-3-METHYLGLUTARIC ACID with the best price .

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